Pre and Post Chemoradiotherapy Assessment of Quality of Life in Individuals Diagnosed with Cervical Cancer in Tripura, India: A Cross-sectional Study

Introduction: Cervical cancer is among the most common malignancies affecting women in India. Assessment of Quality of Life (QoL) has become a vital part of patient care, extending beyond traditional survival outcomes. Despite the high disease burden in Tripura, India limited evidence exists on QoL changes before and after treatment. Aim: To compare the QoL of women with cervical cancer before and after treatment, identify variables influencing QoL, and evaluate the impact of treatment modalities. Materials and Methods: The present cross-sectional study was conducted at the Atal Bihari Vajpayee Regional Cancer Centre, Agartala, Tripura, India, from March 2022 to December 2024. A total of 384 patients were enrolled and reassessed six months after therapy using validated European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQCX24 questionnaires. The data were analysed using Statistical Package for Social Sciences (SPSS) version 24. Paired sample t-tests and Chi-square tests were employed to compare pre and post-treatment EORTC QLQ-C30 and QLQ-CX24 scores, with a significance threshold set at p