An Unusual Synchrony of Bowen’s Disease and Merkel Cell Carcinoma: A Case Report

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Authors: Kewecho Akami, Neikhrietsonuo Kesiezie, Deepak Kharb, Moameren ., Visar Linyu
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Abstract

Bowen’s Disease (BD), recognised as Squamous Cell Carcinoma (SCC) in situ, typically affects older individuals and postmenopausal women, whereas Merkel Cell Carcinoma (MCC) is an aggressive neuroendocrine skin malignancy with a predilection for elderly white males. This case report delves into the unique convergence of BD and MCC in a 45-year-old woman, presenting as BD in the left breast and arm, coupled with MCC in the left wrist with metastasis to the left axilla. The patient was treated with wide local excision of the breast and arm lesions, coupled with en masse clearance of the left axilla due to metastatic MCC. This unique case underscores the intricate interplay between different cutaneous malignancies, emphasising the need for continued research to unravel the underlying mechanisms and optimise therapeutic strategies in rare and challenging dermatological presentations.

Fields of Study & Subjects

Nonmelanoma Skin Cancer Studies Polyomavirus and related diseases Cancer and Skin Lesions

Publication details

Journal / source
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Publication date
8 February 2026
Language
EN