A5208: NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV Transmission (OCTANE) – PLOS 2012

Harvard Dataverse 2026 Dataset Open access

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Authors: ACTG Statistical and Data Analysis Center
DOI: 10.7910/dvn/nycwfq
Cited by: 0

Abstract

Background: Nevirapine (NVP) is widely used in antiretroviral treatment (ART) of HIV-1 globally. The primary objective of the AA5208/OCTANE trial was to compare the efficacy of NVP-based versus lopinavir/ritonavir (LPV/r)-based initial ART. Methods and findings: In seven African countries (Botswana, Kenya, Malawi, South Africa, Uganda, Zambia, and Zimbabwe), 500 antiretroviral-naïve HIV-infected women with CD4

Fields of Study & Subjects

HIV/AIDS drug development and treatment HIV/AIDS Research and Interventions HIV Research and Treatment

Publication details

Journal / source
Harvard Dataverse
Publication date
9 February 2026
Document type
Dataset