FireGate Biotech FG-003: In Silico Systems Analysis Supporting a Coordinated Neuro-Immune Repair Axis
Abstract
This dataset contains STRING-derived protein–protein interaction network outputs and Gene Ontology (GO) enrichment results supporting an exploratory in silico systems-level analysis of neuroinflammatory, inflammasome-associated, microglial, and remyelination-relevant immune signaling pathways related to the FireGate Biotech FG-003 program. The analysis evaluates whether a curated set of genes involved in IL-1 signaling, innate immune activation, microglial biology, and oligodendrocyte lineage function form a statistically enriched and non-random biological network. These results provide computational support for mechanistic convergence across neuroinflammation control and repair-associated pathways. This dataset is intended for hypothesis generation and grant-supporting exploratory analysis.
Fields of Study & Subjects
Neuroinflammation and Neurodegeneration Mechanisms
Multiple Sclerosis Research Studies
Bioinformatics and Genomic Networks
Publication details
- Journal / source
- Harvard Dataverse
- Publication date
- 30 January 2026
- Document type
- Dataset