FireGate Biotech FG-003: In Silico Systems Analysis Supporting a Coordinated Neuro-Immune Repair Axis

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Authors: Daniel Rizzo
Cited by: 0

Abstract

This dataset contains STRING-derived protein–protein interaction network outputs and Gene Ontology (GO) enrichment results supporting an exploratory in silico systems-level analysis of neuroinflammatory, inflammasome-associated, microglial, and remyelination-relevant immune signaling pathways related to the FireGate Biotech FG-003 program. The analysis evaluates whether a curated set of genes involved in IL-1 signaling, innate immune activation, microglial biology, and oligodendrocyte lineage function form a statistically enriched and non-random biological network. These results provide computational support for mechanistic convergence across neuroinflammation control and repair-associated pathways. This dataset is intended for hypothesis generation and grant-supporting exploratory analysis.

Fields of Study & Subjects

Neuroinflammation and Neurodegeneration Mechanisms Multiple Sclerosis Research Studies Bioinformatics and Genomic Networks

Publication details

Journal / source
Harvard Dataverse
Publication date
30 January 2026
Document type
Dataset