Data from: Transcriptomic and methylomic analyses show significant shifts in biosynthetic processes and reduced intrapopulation gene expression variance in PAH-Adapted Atlantic killifish

Environmental contaminants pose a significant selection pressure across taxa, potentiating evolved resistance to chemicals. However, rapid evolution may alter molecular and physiological homeostasis leading to trade-offs. To elucidate molecular underpinnings of evolved chemical resistance, we compared liver gene expression and methylation profiles in polycyclic aromatic hydrocarbon (PAH)-adapted Atlantic killifish (Fundulus heteroclitus) in the Republic site (RP), Elizabeth River, Virginia with PAH-sensitive Kings Creek (KC) fish. Data herein include alternatively spliced genes, differentially expressed genes, methylation, mRNA read counts, sequenced RRBS, and gene ontologies.