Laryngospasm in Pediatric Anesthesia with Intravenous versus Inhalation Anesthetic Induction

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Authors: Lucas Alessi, Jacob Linomaz, Ally E. Spohn, Megan Dekok, Nicholas Rodriguez, Neha Lamsal, Richard Alessi
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Abstract

This review explores the occurrence of laryngospasm following intravenous (IV) administration of propofol versus inhalation induction with sevoflurane in pediatric anesthesia. A structured literature search was conducted using PubMed, MEDLINE, PsycINFO, and CINAHL to identify relevant studies. A total of 14 articles were selected based on predefined inclusion criteria. This review seeks to elucidate the optimal induction method to reduce perioperative respiratory complications, particularly laryngospasm, and improve pediatric patient outcomes. Evidence suggests that IV anesthesia with propofol is associated with a lower incidence of laryngospasm compared to inhalation anesthesia with sevoflurane, especially in patients predisposed to respiratory complications, such as those with upper respiratory infections. Additionally, reduced perioperative complications may lead to cost-effective healthcare outcomes, including decreased hospital admissions. However, in certain clinical scenarios such as patients with difficult IV access or significant needle phobia, inhalation induction may still be preferable. This review highlights the need for further research to better understand the benefits and limitations of IV induction in pediatric anesthesia, while also considering patient-specific factors that influence induction choice.

Fields of Study & Subjects

Anesthesia and Sedative Agents Airway Management and Intubation Techniques Nausea and vomiting management

Publication details

Journal / source
RVU Elevate
Publication date
7 August 2026
Language
EN