Chemical Characterization and Evaluation of the Antioxidant Activity of Ethanolic Extracts from the Leaves of Turnera subulata: An Integrative Literature Review

Aims: To conduct an integrative literature review aimed at quantitatively compiling and analyzing published articles on the medicinal use of Turnera subulata, with emphasis on its phytotherapeutic properties in relation to human pathologies. Study Design: Integrative literature review. Place and Duration of Study: The database collection followed pre-established academic standards and was conducted between October 2024 and January 2026 through searches in scientific databases. Methodology: A systematic search was carried out according to predefined academic criteria. The search initially identified 174 articles. After a rigorous screening process, 144 articles were excluded for not meeting the thematic criteria “Phytotherapeutic properties of Turnera subulata in relation to human pathologies.” A total of 30 articles were selected for inclusion in the results and discussion. The review focused on the identification and chemical characterization of active compounds and the analysis of their biological activities, particularly antioxidant, antimicrobial, and anti-inflammatory effects. Results: The selected studies demonstrate that medicinal plants are an important source for the treatment of various human diseases due to the presence of secondary metabolites with diverse biological activities. The findings indicate that Turnera subulata possesses significant antioxidant, antimicrobial, and anti-inflammatory properties, supporting its traditional use in folk medicine and highlighting its potential phytotherapeutic application in human pathologies. Conclusion: Turnera subulata presents promising phytotherapeutic potential, especially due to its bioactive secondary metabolites and antioxidant activity. The integrative review reinforces the relevance of further scientific investigations to validate its therapeutic effects and support its safe and effective use in the treatment of human diseases.