Uncommon Heartache: The Surprising Discovery of a Cardiac Neuroendocrine Tumor in a Young Adult

Abstract Background: Neuroendocrine tumors (NETs) of the heart are extremely rare and typically arise as metastases from primary gastrointestinal or pulmonary tumors. Their diagnosis can be challenging due to their atypical presentation and the often non-specific symptoms. Case presentation: We present the case of a 20-year-old male patient who was referred for evaluation due to abdominal distension and significant edema of the lower extremities. Diagnostic imaging revealed a hepatic neuroendocrine tumor with an unusual cardiac metastasis localized in the right atrium. The patient also exhibited complications, including deep vein thrombosis and a right lobar pulmonary embolism, which added to the complexity of his clinical management. Conclusion: This case highlights the importance of considering cardiac involvement in patients with neuroendocrine tumors, as well as the diagnostic challenges and therapeutic strategies associated with these atypical metastatic presentations. A multidisciplinary approach is essential for effectively managing such complex cases and improving patient outcomes.