In vivo Evaluation of the Anti-anemic Potentials of Talinum triangulare on Packed Cell Volume and Histopathology in Phenyl Hydrazine-induced Female Wistar Rats

Anemia is a medical condition in which the red blood cells count is less than normal. This study looked at the effect of Talinum triangulare extract (TTE) on phenylhydrazine (PHZ) induced anemic Wistar rats. 30 Female Wistar rats grouped into 5 rats per group were used; group 1 was given 100mg TTE, group 2, 200mg TTE, group 3, 300mg TTE, group 4, 400mg TTE, group 5, administered Bunto blood tonic and group 6, normal saline (control). PHZ was administered to rats intraperitoneally (IP) at a dose of 40 mg/kg of body for two consecutive days. Treatment began after it was certified that the rats were anemic, with packed cell volume (PCV%) of anemic rats taken 24 hours post induction with PHZ. After induction, rats on 400 mg TTE showed the greatest increase in the mean values for PCV count of 41.8%, 41.8% and 45.8% respectively, when compared to the anemic control group with p