Assessment of the levels of oxidative and anti-oxidative stress markers in subjects with cerebrovascular accident

Background: Stroke, a leading cause of global mortality and long-term disability, is characterized by a disturbance in cerebral blood supply, often leading to significant oxidative stress and inflammatory responses. Objectives: This study investigated the levels of oxidative and antioxidative stress markers in cerebrovascular accident (CVA) patients to elucidate their roles in disease progression and potential for intervention. Methods: Sixty CVA patients (30 males, 30 females, aged 40-80 years) and forty age-matched healthy controls were enrolled. Serum concentrations of malondialdehyde (MDA), Vitamin C (Ascorbic acid), and Vitamin E (Alpha-tocopherol) were determined using spectrophotometric methods. Statistical analysis was performed using SPSS version 18, with significance set at p