Surgical Outcomes of Cataract Surgery Following Rapid Glycemic Control During Preoperative Period

Yani Wang,1– 3 Xiaoming Wu,1– 3 Xiaomin Liu,1– 3 Cheng Cheng,1,3 Weina Wang,1,3 Yunhai Dai1– 3 1Department of Cataract, Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, Shandong, People’s Republic of China; 2State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Eye Diseases, Shandong First Medical University, Qingdao, Shandong, People’s Republic of China; 3School of Ophthalmology, Shandong First Medical University, Jinan, Shandong, People’s Republic of ChinaCorrespondence: Yunhai Dai, Department of Cataract, Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, 5 Yan er dao Road, Qingdao, Shandong, 266071, People’s Republic of China, Email yunhaidai@163.comPurpose: To evaluate the effects of rapid preoperative glycemic control on outcomes of cataract surgery for type 2 diabetes patients with high HbA1c levels.Methods: The medical data of consecutive cohort patients with type 2 diabetes who underwent cataract surgery were respectively reviewed between January 2023 and May 2024. The rapid control group consisted of 152 patients (222 eyes) with HbA1c > 9.0% following rapid glycemic control (average duration: 17.3 ± 6.6 days), and the basic control group consisted of 111 patients (162 eyes) with HbA1c < 7.0%. Complications and visual outcomes were analyzed between the two groups during the 6-month postoperative follow-up.Results: Macular edema and vitreous hemorrhage were the main postoperative complications in rapid control group (11.7%) and basic control group (4.9%) (P = 0.021). Linear Mixed-effects Models analysis showed that rapid glycemic correction (Odds ratio [OR] = 6.525, 95% confidence interval [CI] = 2.927– 14.547, P