Interpretation of the "Guideline on positioning and early mobilisation in the critically ill by an expert panel"

ObjectiveTo systematically interpret the "Guideline on positioning and early mobilisation in the critically ill by an expert panel".MethodsThe development background,evidence quality,and key recommendations of the guideline were systematically reviewed.The focus was placed on interpreting the core recommendations regarding positioning and early mobilisation,and clinical practice considerations aligned with China's national context were proposed accordingly.ResultsThe guideline put forward 46 recommendations,encompassing 23 on positioning management,19 on early mobilisation,4 on assistive devices,and 2 on neuromuscular electrical stimulation.Key recommendations included:head⁃of⁃bed elevation≥40° for intubated patients;early initiation of prone positioning ventilation(for at least 12 hours) in ARDS patients with PaO₂/FiO₂