A001: Electronic Health Interventions on Promoting Physical Activity in Patients with Type 2 Diabetes: A Meta-Analysis

The prevalence of diabetes mellitus is increasing year over year, and its high number of complications and disability rates pose a significant challenge to global public health. Electronic health has achieved better efficacy in patients with type 2 diabetes, but research in promoting exercise in diabetes is incomplete. A computerized search of Web of science, PubMed, The Cochrane Library, and Embase databases was conducted to retrieve randomized controlled trials (RCTs) of e-health interventions for physical activity in patients with type 2 diabetes. The risk of bias of the included literature was assessed according to ROB 2.0. Heterogeneity of study results was detected by I², and subgroup meta-analysis were used to find sources of heterogeneity. Sensitivity analyses assessed the stability of results. Meta-analysis was performed using Stata 15.0. A total of 14 RCTs with 1,385 patients were included. Meta-analyses showed that the test group significantly improved physical activity (SMD: 0.35; 95% Cl: 0.22, 0.49) and reduced glycated hemoglobin (WMD：0.74；95%Cl：0.34，1.14), BMI (WMD: 0.74; 95% Cl: 0.36, 1.12), and waist circumference (SMD: 0.49; 95% Cl: 0.05, 0.93; all P’s < 0.05) but did not significantly reduce the levels of blood lipids (Cholesterol, Triglyceride, HDL-c, and LDL-c; all P’s > 0.05). E-health interventions can improve physical activity and reduce glycated hemoglobin, BMI and waist circumference in patients with type 2 diabetes mellitus. These conclusions still need to be confirmed with larger sample sizes and high-quality studies.