Mitochondrial Stability in Cardiomyocytes Under Extreme Stress: Mitophagy–Biogenesis Coupling Across Special Reconnaissance and Triathlon Endurance, with Translational Links to Longevity, Cancer Biology, and Modern High-Tempo Conflict Resilience Working Paper / Preprint | Version 1.2

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Authors: Brian Nielsen
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Abstract

Appendix A to NMRI Paper v1.2 20 research directions (hypotheses and recommendations) on mitochondrial stability in cardiomyocytes: mitophagy–biogenesis–balance Triathlon • Longevity • Oncology • Operational & cognitive resilience (including drone-era environments) Date: 2026-01-13 | NMRI | ORCID (Brian Nielsen): 0009-0002-4914-354X Scope: A hypothesis-generating document based on synthesis of the scientific literature, analyses, and the authors’ NMRI observations. It is not medical advice and it is not operational instruction; battlefield specifics are intentionally generalized. The intent is to propose testable research directions for academic and defense research centers (USA/Poland).

Fields of Study & Subjects

Autophagy in Disease and Therapy Mitochondrial Function and Pathology Cell death mechanisms and regulation

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
14 January 2026
Document type
Preprint