The association of neonatal 25 hydroxyvitamin D and vitamin D-binding protein levels with subsequent asthma

OSF Preprints (OSF Preprints) 2026 Preprint

Authors: Henriette Thisted Horsdal, Bo Chawes, Klaus Bønnelykke, John Joseph McGrath, Carsten Bøcker Pedersen, Zhihong Zhu, Xiaoqin Liu
Cited by: 0

Abstract

In this cohort study, we will examine the associations of neonatal 25OHD and DBP levels with the subsequent risk of developing asthma. We hypothesize that low 25OHD and DBP levels independently and jointly contribute to an elevated risk of developing asthma later in life. Furthermore, we will examine potential gene-environment interplay that include both the influence of 25OHD and DBP and polygenic risk scores of asthma and individual candidate genes.

Fields of Study & Subjects

Vitamin D Research Studies Asthma and respiratory diseases Genetic Associations and Epidemiology

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
27 January 2026
Document type
Preprint