Targeting Undruggable Targets: Protein Degradation (PROTACs), Molecular Glues, and Allosteric Inhibition
Abstract
ChaptersChapter 1: Targeting Undruggable Oncogenic Proteins in Women's Cancers: Mechanisms of Protein Degradation via PROTACs and Molecular Glues in Breast and Ovarian Malignancies (Hasna Zarkhah)Chapter 2: Molecular Medicine Approaches in Oncology: Harnessing PROTACs, Molecular Glues, and Allosteric Inhibitors for Precision Targeting of Undruggable Cancer Drivers (Behnoosh Rafieyan)Chapter 3: Integrating Artificial Intelligence in Women's Cancer Therapeutics: AI-Driven Design and Optimization of PROTACs, Molecular Glues, and Allosteric Modulators for Undruggable Targets (Elham Nedaei)Chapter 4: Advanced Oncology Treatments: Efficacy and Challenges of Protein Degradation Strategies, Including PROTACs and Molecular Glues, Combined with Allosteric Inhibition in Cancer Therapy (Fatemeh Jamali)Chapter 5: Artificial Intelligence Applications in Cancer Drug Discovery: Computational Modeling and Prediction of PROTAC-Mediated Degradation, Molecular Glue Interactions, and Allosteric Inhibition for Undruggable Targets (Saeid Bolhasani)Chapter 6: Emerging Research Trends in Cancer: Novel PROTAC Designs for Ubiquitin-Proteasome System Exploitation in Targeting Previously Undruggable Proteins (Arash Kiani)Chapter 7: Current Trends in Cancer Research: Molecular Glues as Innovative Tools for Inducing Protein-Protein Interactions and Degradation in Undruggable Oncogenic Pathways (Matin Talei)Chapter 8: Future Directions in Cancer Research Trends: Allosteric Inhibition Strategies and Their Synergy with PROTACs and Molecular Glues for Overcoming Drug Resistance in Undruggable Targets (Sajad Khonche)
Fields of Study & Subjects
Protein Degradation and Inhibitors
Computational Drug Discovery Methods
Chemical Synthesis and Analysis
Publication details
- Journal / source
- HAL
- Publication date
- 1 January 2026
- Language
- EN
- Document type
- Book