Community and Individual Risk Factors Associated with Tuberculosis Treatment Outcomes: CA, MD, and OH, [2017-2021].

There are unsuccessful treatment outcomes with Tuberculosis (TB) disease, although effective therapies exist. This study aimed to identify predictors of unsuccessful treatment using the socioecological model. A quantitative cross-sectional study and multinomial logistic regression analysis were used to measure the associations between long-term care (LTC), homelessness, correctional facility, Human Immunodeficiency Virus (HIV), diabetes, excess alcohol, illicit drug use, and TB treatment outcomes of death, lost to follow-up, and treatment refusal. The sample consisted of 7,589 individuals aged 15 and older with pulmonary TB between 2017 and 2021, residing in California, Ohio, and Maryland. Findings indicated a correlation between community factors (LTC, homelessness, correctional facility), individual factors (HIV, illicit drugs), and TB treatment outcomes. Homelessness was a predictor of death (Exp(B)=1.75, 95% CI :1.24-2.48, p=.001), loss to follow-up (Exp(B)=4.55,95% CI: 2.82-7.33; p