[Arterial embolism in a patient's feet].
Abstract
A 69-year-old woman presented with progressive gangrene affecting the toes of both feet. Laboratory investigations showed marked thrombocytosis (800 x 109/l). A positive JAK2V617F-mutation confirmed essential thrombocytosis as the underlying cause of the gangrene. With thrombocyte-lowering therapy, platelet counts normalized and the gangrene showed no further progression.
Fields of Study & Subjects
Myeloproliferative Neoplasms: Diagnosis and Treatment
Platelet Disorders and Treatments
Peripheral Artery Disease Management
Publication details
- Journal / source
- PubMed
- Volume
- 70
- Publication date
- 28 January 2026
- Language
- NL