RNA-seq of cortical synaptoneurosomes from MNK1 and MNK2 KO mice

MDC Repository (Max-Delbrueck-Center for Molecular Medicine) 2026 Dataset

Authors: D. Bunina, H. Hörnberg
Cited by: 0

Abstract

The experiment was designed to study which genes are differentially expressed on mRNA level in MNK1 or MNK2 KO mice, focusing on synaptic compartment, and further correlate these genes with mis-expressed proteins in the same genotype mice. This would reveal whether MNK1 or MNK2 KOs mostly affect transcriptional or post-transcriptional programs in the neurons.

Fields of Study & Subjects

Genetics and Neurodevelopmental Disorders Neuroscience and Neuropharmacology Research RNA Research and Splicing

Publication details

Journal / source
MDC Repository (Max-Delbrueck-Center for Molecular Medicine)
Publication date
10 February 2026
Language
EN
Document type
Dataset