A glutamatergic Sp5C-STN circuit mediates chronic migraine in mice.
Abstract
-STN circuit in the development and modulation of CM. Our findings provide novel mechanistic insights into the central mechanisms underlying CM, establishing potential theoretical foundations for clinical diagnosis and therapeutic development.
Fields of Study & Subjects
Migraine and Headache Studies
Pain Mechanisms and Treatments
Neuroscience and Neuropharmacology Research
Publication details
- Journal / source
- PubMed
- Volume
- 78
- Issue
- 1
- Pages
- 159–172
- Publication date
- 25 February 2026
- Language
- EN