[Molecular mechanism of HNRNPC mediated ferroptosis in Ang II-related coronary heart disease].

PubMed 2026

Authors: Qingling Hu, Qi Tang, Zhouzhan Luo, Guolong Lei, Qiaofeng Wang, Chao Peng
Cited by: 1

Abstract

, total Fe, MDA, 4-HNE and HNRNPC protein in Ang II group increased significantly, and the level of FTH1 protein decreased significantly, and those changes were reversed significantly in Fer-1+Ang II group. Conclusions The imbalance of iron homeostasis mediated by HNRNPC/FTH1 signaling pathway may drive Ang II-induced cardiac ferroptosis.

Publication details

Journal / source
PubMed
Volume
42
Issue
1
Pages
36–44
Publication date
1 January 2026
Language
ZH