Unveiling Noradrenaline: Insights into Cardiac Autonomic Neuropathy in a Type 1 Diabetic Animal Model

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Authors: Shamala Devi Subramaniam, Nurulaidah Esa, Noorkardiffa Syawalina Omar, Razif Abas
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Abstract

BACKGROUND: The global surge in Type 1 Diabetes Mellitus (T1DM) cases across age groups has raised concerns about associated cardiovascular risks, warranting a deeper understanding of its complications. Diabetic Cardiovascular Autonomic Neuropathy (DCAN), characterized by cardiovascular system irregularities in diabetic patients, remains inadequately explored, particularly in T1DM. This study aimed to establish a connection between T1DM and the onset of DCAN in an animal model, focusing on the role of noradrenaline as a potential marker.

Fields of Study & Subjects

Heart Rate Variability and Autonomic Control Diabetes Management and Research Cardiovascular Syncope and Autonomic Disorders

Publication details

Journal / source
Malta Medical Journal
Publication date
1 January 2026
Language
EN