Specific Circulating and Urinary MicroRNAs (miR-132, miR-133a, miR-203, miR-196-3p, miR-155) as Early Predictors of Microvascular Complications (Nephropathy, Retinopathy, Neuropathy) in Type 2 Diabetes: A Systematic Review and Meta-Analysis

OSF Preprints (OSF Preprints) 2026 Preprint

Authors: Omer Abdelazim, Adnan Raad Al-obaidi, Saad Hasan Malik, Rana Mouaki Benani Chebihat, Jeevan K. Shetty, Bindhu Nair, Sirine Zamouri, Ibrahim Raed Fakhri
Cited by: 0

Abstract

This systematic review aims to elucidate the role of specific circulating and urinary microRNAs (miR-132, miR-133a, miR-203, miR-196-3p, miR-155) as biomarkers for predicting microvascular complications (Nephropathy, Retinopathy, Neuropathy) in individuals with type 2 diabetes. The findings may provide insights into novel noninvasive diagnostic tools for early intervention in microvascular complications associated with diabetes.

Fields of Study & Subjects

MicroRNA in disease regulation Chronic Kidney Disease and Diabetes Extracellular vesicles in disease

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
4 March 2026
Language
EN
Document type
Preprint