Safety Evaluation in Phase I Clinical Trials of Herbal Interventions: A Scoping Review

OSF Preprints (OSF Preprints) 2026 Preprint

Authors: Nahathai Dukaew, Mingkwan Na Takuathung, Aiyarin Kittilukkana, Nut Koonrungsesomboon
Cited by: 0

Abstract

This scoping review maps and synthesizes existing evidence on how safety is evaluated in Phase I clinical trials of herbal interventions. The review focuses on study design, safety assessment approaches, and reported safety outcomes, aiming to provide a structured overview of current safety evaluation strategies in early-phase herbal research.

Fields of Study & Subjects

Complementary and Alternative Medicine Studies Phytochemistry Medicinal Plant Applications Statistical Methods in Clinical Trials

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
4 March 2026
Language
EN
Document type
Preprint