Identification of conserved frontal neurophysiological markers of cognitive flexibility in humans and rats

OSF Preprints (OSF Preprints) 2026 Preprint Open access

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Authors: Hongyi Pan, Zeyun Wu, Hans Schroder, Ann Mary Iturra-Mena, Emilia F. Cárdenas, Daniel G. Dillon, Samuel A. Barnes, Ty Lees, Eran A. Mukamel, William A. Carlezon, Diego A. Pizzagalli, Samantha R. Linton
+12 more Sarah Perlo, Brian D. Kangas, Mykel A. Robble, Micah Breiger, Andre Der‐Avakian, Jack Bergman, Rachel Lobien, Victoria B. Risbrough, Stefan Leutgeb, Genevieve P. Nowicki, Stefanie Nickels, James P. Kesby
Cited by: 0

Abstract

This project used versions of a probabilistic reversal learning task aligned between humans and rats to conduct a a systematic cross-species comparison of behavioral, neurophysiological, and computational markers of cognitive flexibility.

Fields of Study & Subjects

Neural and Behavioral Psychology Studies Neurotransmitter Receptor Influence on Behavior Memory and Neural Mechanisms

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
13 March 2026
Language
EN
Document type
Preprint