Tailored Multimodal Therapeutic Regimen for Neurodermatitis: Alleviating Skin Excoriation Urges through an Interdisciplinary Approach.

Background: Neurodermatitis significantly impairs quality of life due to the chronic itch-scratch cycle driven by compulsive excoriation behavior. Objective: This study evaluated the effectiveness of a tailored therapeutic regimen in reducing excoriation behavior and improving patient outcomes. Research Design: Quasi-experimental study conducted over six weeks. Setting: The study was conducted at selected dermatology clinics in Pune, Maharashtra, India. Participants: Sixty adult participants diagnosed with neurodermatitis were recruited and divided into experimental (n=30) and control (n=30) groups using multistage cluster sampling. Intervention: The intervention group received a structured, patient-centered therapeutic kit including an instructional pamphlet. Primary Outcome Measures: Pre- and post-intervention assessments were conducted using the 5-D Pruritus Scale. Results: Baseline mean urge score in the experimental group was 17.8 (SD = 1.3), indicating severe to unbearable excoriation tendencies. Post-intervention, the experimental group's mean urge score significantly decreased to 12.2 (SD = 1.1), indicating a shift toward moderate urge levels (P < .001). In contrast, the control group showed no significant improvement. Additionally, participants in the intervention group reported enhanced quality of life scores and average satisfaction with the regimen. The tailored therapeutic regimen significantly reduced excoriation behavior among individuals with neurodermatitis. Conclusion: These findings support the integration of behavioral and dermatological strategies in routine clinical management to disrupt the itch-scratch cycle and improve patient well-being. keywords: tailored multimodal therapeutic regimen, neurodermatitis, excoriation, excoriation behavior alleviation.