[Helicobacter pylori eradication and associated factors: dual therapy versus standard triple therapy in Lima, Peru].

OBJECTIVE: Helicobacter pylori (H. pylori) infection is the most important risk factor for gastric cancer development. Dual therapy can achieve higher eradication rates than standard triple therapy, and the factors associated with lower eradication rates have not been fully studied. The objective of our study was to evaluate the H. pylori eradication rate and its associated factors using dual therapy versus standard triple therapy. MATERIALS AND METHODS: This retrospective cohort study included 1,506 patients with H. pylori infection who received dual therapy or standard triple therapy. Eradication was confirmed with urea breath test. Chi-square (χ) test was used to analyze categorical variables, and relative risk (RR) was used to assess associations between eradication rates and clinical variables. RESULTS: Eradication was higher with dual therapy, with 84.58% (384/454) versus 73.86% (777/1052) with standard triple therapy (p