Influencia de los protocolos preventivos durante la extracción dental en la aparición de osteonecrosis de la cavidad oral asociada a medicamentos: revisión sistemática paraguas

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Authors: Hernández Álvarez, Arlteh Sandry, Vega Gutiérrez, Maryury, Carbonell Muñoz, Zoila, Plazas Román, Jaime, Díaz Caballero, Antonio José
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Abstract

Introduction: Medication-related osteonecrosis of the oral cavity (MRONJ) is a severe complication in patients receiving antiresorptive therapy, with incidence ranging from 0,01-0,10% in osteoporosis and up to 6,70% in cancer patients. Objective: To identify through an umbrella systematic review (2019-2024) the influence of preventive protocols during dental extractions on the occurrence of MRONJ. Methodology: Systematic search in PubMed, EBSCO and Scopus following PRISMA guidelines. Systematic reviews on dental extraction in patients at risk for MRONJ were included. Quality assessed using JBI checklist. Results: Eight reviews were analyzed (23.209 patients, 264 studies) with low heterogeneity (I²=

Fields of Study & Subjects

Bone health and treatments Oral health in cancer treatment Oral Health Pathology and Treatment

Publication details

Journal / source
Dialnet (Universidad de la Rioja)
Publication date
1 January 2026
Language
ES