Imaging biomarkers for early detection, monitoring and prediction of treatment-related side effects in radiotherapy – A scoping review

OSF Preprints (OSF Preprints) 2026 Preprint Open access

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Authors: Peter van Luijk, Robert Jeraj, Laia Humbert-Vidan, Tiziana Rancati, Natalie West, Jane Shortall, Clifton David Fuller, Azadeh Abravan, Giulia Rambaldi Guidasci, Claudio Fiorino, Eliana Gioscio, David Farris
+1 more Vanessa Panettieri
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Abstract

This scoping review aims to assess the current landscape of imaging biomarkers developed for the detection, monitoring and prediction of treatment-related side effects to inform treatment adaptation for improved patient outcomes in radiation therapy. It seeks to identify the types of imaging biomarkers utilized, their clinical applications, and the extent of their validation (and clinical translation) in detecting, monitoring and predicting radiation-induced toxicities.

Fields of Study & Subjects

Effects of Radiation Exposure Radiomics and Machine Learning in Medical Imaging Advanced Radiotherapy Techniques

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
20 September 2026
Document type
Preprint