The Role of Therapeutic Plasma Exchange in Treatment of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy.

PubMed 2026

Authors: Yiğit Baykara, Liqi Shu, Yamac Akgün
Cited by: 0

Abstract

Key Ideas Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a recently identified inflammatory central nervous system (CNS) disorder marked by GFAP-IgG autoantibodies. Therapeutic plasma exchange (TPE) removes pathogenic autoantibodies, cytokines, and immune complexes, thereby targeting the disease's core immunopathology. TPE is a rational and potentially lifesaving therapy in autoimmune GFAP astrocytopathy, especially in refractory or life-threatening cases.

Fields of Study & Subjects

Autoimmune Neurological Disorders and Treatments Peripheral Neuropathies and Disorders Salivary Gland Disorders and Functions

Publication details

Journal / source
PubMed
Volume
109
Issue
1
Pages
19–21
Publication date
5 January 2026
Language
EN