the potential of mango leaf extract (mangifera indica) against melanoma skin cancer

Melanoma skin cancer is one of the most lethal forms of cancer, characterized by its high aggressiveness, rapid metastasis, and resistance to conventional therapies. Current treatment strategies, such as surgery, chemotherapy, radiotherapy, and immunotherapy, often face limitations due to adverse side effects, recurrence, and the development of drug resistance. These challenges highlight the urgent need to explore novel therapeutic approaches, particularly those derived from natural products that are more biocompatible and potentially safer. One promising candidate is the mango leaf (Mangifera indica), a plant widely distributed in tropical regions and traditionally used for various medicinal purposes. Mango leaves are rich in bioactive compounds, including mangiferin, quercetin, flavonoids, and polyphenols, which have been reported to exhibit strong antioxidant, anti-inflammatory, and anticancer properties.